Search on: BETA-PROTEIN PRECURSOR, AMYLOID 
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Descriptor English:   Amyloid beta-Protein Precursor 
Descriptor Spanish:   Precursor de Proteína beta-Amiloide 
Descriptor Portuguese:   Precursor de Proteína beta-Amiloide 
Synonyms English:   Amyloid A4 Protein Precursor
Amyloid Protein Precursor
Amyloid beta Precursor Protein
Amyloid beta Protein Precursor
Nexin 2, Protease
Nexin II, Protease
Protease Nexin 2
Protease Nexin II
beta Amyloid Protein Precursor
beta-Amyloid Protein Precursor
beta-Protein Precursor, Amyloid  
Tree Number:   D12.776.049.407.249
D12.776.543.039
D12.776.645.468.500
D12.776.811.050
Definition English:   A single-pass type I membrane protein. It is cleaved by AMYLOID PRECURSOR PROTEIN SECRETASES to produce peptides of varying amino acid lengths. A 39-42 amino acid peptide, AMYLOID BETA-PEPTIDES is a principal component of the extracellular amyloid in SENILE PLAQUES. 
History Note English:   92; was AMYLOID BETA PROTEIN PRECURSOR (NM) 1988-91; AMYLOID A4 PROTEIN PRECURSOR was NM 1987-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30268 
Unique Identifier:   D016564 

Occurrence in VHL:
 

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